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Hyaluronic acid from Bacillus subtilis

Hyaluronic acid (HA) fillers owe their popularity to good results, low intrusiveness and safe application. However, there are rare cases where a patient’s body reacts to them against expectations.

Why does this happen?

Currently, the most popular source of HA are laboratory strains of Streptococcus.

In fact, extracting the precious acid out of them requires the bacteria membrane breaking and application of chemical solvents. Contaminants present in the finished product are precisely the residues of bacteria and solvents. Despite several purifying processes, today’s technology is unable to fully eliminate these impurities. 


The purest form of hyaluronic acid currently available is obtained from Bacillus subtilis. This bacterium, which is non-pathogenic to humans, produces HA in a process based on water usage.

Unquestionable advantages of Bacillus Subtilis Hyaluronic Acid:

  • Ultra purity

  • High safety of application

  • Pre-determined molecular mass

  • Possibility to apply high HA concentration

  • Long shelf life


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