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Safety and effectiveness of fillers also depends on how they are stabilised. Usually, a BDDE (a cross-linking agent) is used for this purpose. 
Due to its toxicity, it is assumed that the lower its content is, the safer is the product. However, low amount of cross-linker reduces longevity and performance in the tissue.

No more choosing between safety and permanent effect

While others wonder how to reduce the content of undesired substances, the scientists working on Neauvia Organic fillers decided to apply a new crosslinker PEG polymer (not a common monomer like DVS or BDDE used in all the other products on the market). PEG is a well-known polymer on the pharmaceutical market, but it has been used for the first time in filler production by Neauvia.

PEG outstanding advantages:

  • Not-toxic and completely degradable in the tissues
  • Reduces the action of proteolytic enzymes, like hyaluronidase, increasing the longevity of the implant
  • Stops the immunological reaction, as the implants is not recognized as a foreign body

PEG makes Neauvia Organic the most biocompatible fillers on the market reducing almost to zero the biopotential rejection of the hosting tissues. 

Protective action of PEG is able to mask the implant from the host organism reducing the risk of immunological reaction and formation of the foreign body giant cells (FBGC). In other words, PEG reduces inflammation and granulomas formation.

Moreover, it delays the degradation and the bioabsorbtion of the implant.

PEG makes Neauvia fillers the first, one and only BIOMIMETIC fillers worldwide. 


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